Food Grade Inositol is a substance similar in structure to glucose, found in various foods (especially whole grains and citrus fruits). Known as one of the vitamin B groups. So what is an inositol used for?
1. Inositol is beneficial for blood pressure regulation
We know that hypertension is the single largest risk factor for the global burden of disease
Age, excess sodium intake, insufficient dietary potassium intake, overweight and obesity, alcohol consumption, genetic predisposition, and physical inactivity are all associated with the development of hypertension. A systematic literature review and meta-analysis (including 7 randomized controlled trials, with a total of 322 participants) showed that inositol significantly reduced systolic and diastolic blood pressure levels. Subgroup analysis (Subgroup analysis) showed that the relevant blood pressure lowering effect was more significant in patients with metabolic syndrome, with a longer duration (>8 weeks), and with a dose of 4000 mg.
2. Inositol beneficial for retinopathy of prematurity
Retinopathy of prematurity was described in the 1940s as omental fibroplasia. It is defined as a progressive disease that occurs only in premature infants with low birth weight and is characterized by the formation of fibrous tissue behind the lens, leading to blindness and severe visual impairment. Retinopathy of prematurity may be a window into postnatal development in preterm infants. It frequently occurs with other neonatal disorders such as neurological deficits, brain dysplasia, necrotizing enterocolitis, ventricular hemorrhage, and bronchopulmonary dysplasia, and is associated with other ocular problems.
A systematic literature review and meta-analysis found that, compared with a placebo, inositol supplementation did not significantly improve the incidence of severe retinopathy of prematurity, mortality, all stages of the disease, and other adverse events.
3. Food Grade Inositol and polycystic ovary syndrome
Polycystic Ovary Syndrome is a common hormonal abnormality disease in women of reproductive age, with a prevalence rate of about 7%. It is often related to an abnormal increase of androgen and abnormal secretion of gonadotropin, and symptoms such as irregular menstruation, hirsutism, ovulation abnormality, and hair loss. In addition to symptoms related to the reproductive system, another important feature of polycystic ovary syndrome is the abnormal action of pancreatic beta cells and insulin, which increases the incidence of type 2 diabetes
A systematic literature analysis pointed out that the use of inositol can help improve metabolic indicators, increase sex hormone-binding globulin (SHBG), and reduce androgen excess.
4. Inositol and gestational diabetes
Gestational diabetes is mainly defined as pregnancy-related glucose intolerance events, with a prevalence of about 2% to 5%, and the main risk factors are a familial predisposition, age, obesity, history of spontaneous abortion, polycystic ovary syndrome, and essential hypertension wait.
The reason why it is important to prevent gestational diabetes is that high blood sugar during pregnancy is often associated with abnormal growth of the fetus, which not only increases the chance of macrosomia and birth defects but also increases the risk of obesity and diabetes in the future. A meta-analysis of the literature pointed out that supplementing Myo-inositol can reduce the chances of pregnant women developing gestational diabetes mellitus and related adverse events in pregnancy, such as respiratory distress syndrome, shoulder dystocia, neonatal hypoglycemia, macrosomia, and polyhydramnios, premature birth.
5. Inositol and PMS
The premenstrual dysphoric disorder is a more serious form of premenstrual syndrome. The main symptoms are depression, anxiety, mood swings, and decreased interest in activities, and it seriously affects the family, society, and occupational areas.
Estimated by the prevalence and duration of symptoms, the burden of disease caused by PMS is comparable to that of other common mental illnesses.
A randomized double-blind controlled study showed that inositol can help improve symptoms of irritability and depression associated with premenstrual discomfort.
6. Food Grade Inositol and Respiratory Distress Syndrome
Most respiratory distress syndrome is caused by insufficient pulmonary surfactants. These active substances are necessary to reduce the surface tension of the alveoli and maintain their stability of the alveoli. If they are deficient, they will lead to respiratory disorders and various complications, which is one of the main reasons for the increase in neonatal mortality. 1. The incidence rate is between 6% and 7%, especially in premature babies born before 28 weeks.A literature meta-analysis (including 4 randomized controlled trials) pointed out that inositol can reduce the adverse outcomes of respiratory distress syndrome in premature newborns.
JOYWIN founded in 2013 is an innovation-driven biotechnology company. We provide the manufacture of plant extracts, plant proteases, and customized products. If you want to know more about Food Grade Inositol or are interested in purchasing it, you can send an email to contact@joywinworld.com. We will reply to you as soon as possible after you see the message.